Designed Protein and Antibody Nanocage Models from a 2021 Science Paper

A 2021 collection of computational models and scripts supporting the research article "Designed proteins assemble antibodies into modular nanocages" published in Science. The data package includes design models, building blocks, symmetry definitions, and example scripts for creating protein fusions and rendering figures. It was created by Robby Divine at the University of Washington.

Use Cases

• Reproducing computational protein design workflows based on the provided scripts and models.
• Analyzing designed protein structures for nanocage assembly based on the included design models.
• Creating visualizations of protein-antibody complexes using the supplied PyMOL rendering scripts.
• Developing new fusion proteins based on the example scripts for making fusions.

Strengths

• Directly supports a peer-reviewed article published in Science in 2021.
• Includes multiple file types such as design models, scripts, and symmetry definitions for a complete workflow.

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count and dataset size are unknown, which may limit suitability assessment.

Provenance

Source

University of Washington, associated with the research article in Science.

Collection Method

Computational design and modeling, likely generated as part of the published research.

Time Range

2021