MESA: Sex Hormones and NT-proBNP Biomarker Data

Wendy Ying of Johns Hopkins University published supplemental data for a study on sex hormones and N-terminal pro-B-type natriuretic peptide (NT-proBNP). The analysis involved 2,371 postmenopausal women and 2,688 men from the Multi-Ethnic Study of Atherosclerosis (MESA). It includes cross-sectional and longitudinal associations between sex hormone patterns and NT-proBNP levels.

Use Cases

• Analyze cross-sectional associations between sex hormone patterns and NT-proBNP levels based on the study's findings.
• Model longitudinal changes in NT-proBNP levels in relation to hormonal profiles based on the described longitudinal analysis.
• Investigate potential mechanisms for increased CVD risk in postmenopausal women based on the described hormonal associations.
• Replicate or extend the study's statistical analysis of androgenic hormone patterns and biomarker levels.

Strengths

• Data is associated with a peer-reviewed publication, providing academic context.
• Study includes a substantial cohort of 5,059 participants (2,371 women and 2,688 men).
• Analysis covers both cross-sectional and longitudinal associations.

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Johns Hopkins University

Collection Method

Clinical data collection from the Multi-Ethnic Study of Atherosclerosis (MESA).