Data files for "<b>Larval habitat drives differential selection pressures on genetic insec

Tabular data from a laboratory colonization experiment tracking insecticide resistance in Anopheles gambiae mosquitoes. The dataset includes phenotypic susceptibility bioassays, target-site mutation frequencies, and metabolic enzyme activities across 11 generations (F0 to F10) under three larval water treatments. It was authored by Ibrahim K. Gyimah and last updated on 2026-05-29.

Use Cases

• Modeling the fixation rate of the kdr-w allele based on larval water treatment.
• Analyzing the relationship between water physicochemical profiles and baseline metabolic enzyme levels.
• Studying the generational decline of kdr-w frequency in a colony maintained without insecticide pressure.
• Investigating phenotypic plasticity in mixed-function oxidase activity driven by natural environmental co-factors.

Strengths

• Data spans 11 successive generations (F0 to F10) of laboratory colonization.
• Includes four insecticide classes and synergist exposures with piperonyl butoxide (PBO).
• Tracks two target-site mutations (kdr-w and ace-1) and four detoxification enzyme activities.
• Compares three distinct larval water treatments: field-collected, tap, and distilled water.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single urban collection site in Accra, Ghana, which may limit geographic generalizability.

Provenance

Source

figshare

Collection Method

Wild Anopheles gambiae s.l. larvae were collected, colonized, and maintained in the laboratory. Phenotypic resistance was assessed via WHO tube bioassays, with molecular genotyping and biochemical enzyme activity monitoring.

Time Range

Covers 11 laboratory generations (F0 to F10).

Freshness

Last updated 2026-05-29 07:38:11; freshness should be verified.

Geography

Larvae were collected from a single urban site in Accra, Ghana.