Enteric Glial Cell Cytokine and Growth Factor Response to Short Chain Fatty Acids

A collection of raw qPCR and Western immunoblotting data from a study on how butyrate and propionate modulate mRNA and protein levels of specific growth factors and pro-inflammatory cytokines in isolated enteric glial cells. The data supports a manuscript under review by author Danielle Defries. Row count, column count, and sample size are not specified in the input.

Use Cases

• Analyze the modulation of glial cell line-derived neurotrophic factor mRNA levels in response to butyrate treatment.
• Compare protein expression levels of pro-inflammatory cytokines TNFalpha, IL-6, and IL-1beta between propionate and control conditions.
• Investigate correlations between mRNA and protein data for transforming growth factor beta across different short chain fatty acid treatments.

Strengths

• Data is directly linked to a specific, detailed manuscript under review, providing clear experimental context.
• Includes measurements for multiple specific biological targets: two growth factors and three pro-inflammatory cytokines.
• Data was last updated on January 31, 2026, indicating recent maintenance.

Limitations

• The dataset's size, structure (e.g., row/column count), and file formats are unknown, complicating assessment of its analytical scope.
• As raw experimental data from a specific lab study, it may have a limited sample size not suitable for large-scale machine learning.
• The data is focused on isolated enteric glial cells, which may limit generalizability to in vivo or other cell type contexts.

Provenance

Source

Borealis Harvested Dataverse

Collection Method

Raw qPCR and Western immunoblotting data collected from laboratory experiments on isolated enteric glial cells.

Freshness

Last updated on 2026-01-31.