Rat Hippocampus 3D Electron Microscopy Data for Synaptic Bouton Analysis

A 3D electron microscopy dataset acquired from adult rat hippocampal area CA1, stratum radiatum. The data supports the paper 'Presynaptic vesicles supply membrane for axonal bouton enlargement during LTP' and includes serial section EM images, 3D Blender objects, and quantitative spreadsheets. The dataset was authored by Lyndsey Kirk and last updated on October 15, 2025.

Use Cases

• Reconstructing 3D synaptic bouton morphology based on provided serial section EM images and Blender files.
• Analyzing presynaptic vesicle dynamics and membrane supply during LTP based on quantitative data extracted from image analysis.
• Validating computational models of synaptic plasticity using the included statistics and measurement files.
• Reproducing the figures and analyses from the associated manuscript using the original code and data.

Strengths

• Includes original analysis code, facilitating full reproducibility of the published research.
• Provides multiple data modalities: raw EM images, 3D reconstruction files, and processed quantitative spreadsheets.
• Dataset is explicitly linked to a peer-reviewed publication, providing clear context and validation.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count and total dataset size are unknown, which may limit suitability assessment.

Provenance

Source

Texas Data Repository Harvested Dataverse

Collection Method

3D electron microscopy imaging of adult rat hippocampal tissue.

Time Range

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Freshness

Last updated 2025-10-15 06:50:51; freshness should be verified.

Geography

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