Medicinal Leech Ganglion Membrane Potential Imaging Data

2020 data from a study by Yusuke Tomina applying a double-sided voltage-sensitive dye microscope to the segmental ganglia of the medicinal leech Hirudo verbana. The dataset contains simultaneous recordings of membrane potential dynamics from nearly all identifiable neurons in the ganglion, enabling analysis of neuronal network activity during sensory processing and motor control.

Use Cases

• Construct functional maps of neuronal activity by analyzing membrane potential event sequences from identified neurons.
• Analyze correlations in membrane potential dynamics across neurons to study network emergence during sensory processing.
• Validate the double-sided voltage-sensitive dye imaging technique for whole-ganglion recording by examining signal quality from simultaneous two-sided captures.

Strengths

• Data originates from a novel double-sided microscope technique enabling simultaneous imaging of two sides of a nervous system.
• Recordings capture membrane potential events from almost all identifiable neurons within the leech segmental ganglion.
• Data is licensed under CC0-1.0, allowing for unrestricted reuse and analysis.

Limitations

• The dataset scope is limited to the specific model organism Hirudo verbana, limiting generalizability to other species.
• Specific technical details like file formats, data size, and the exact number of recordings or neurons are not provided in the input.
• Data is from a single study published in 2020 and may not reflect the latest methodological advancements.

Provenance

Source

Dryad digital repository.

Collection Method

Recorded using a custom-developed double-sided voltage-sensitive dye (VSD) imaging microscope applied to leech segmental ganglia.

Freshness

Last updated on 2020-06-24.