Mouse Auditory Pathway Responses to Ultrasonic Vocalizations

2020 research data contains evoked potential, single-unit, and multi-unit neural recordings from the mouse auditory nerve, cochlear nucleus, and inferior colliculus. The dataset supports analysis of auditory processing specialization for high ultrasonic frequencies above 32 kHz. It was created by Jose A. Garcia-Lazaro to investigate mechanisms underlying vocalization perception.

Use Cases

• Compare evoked potential response amplitudes between auditory nerve and inferior colliculus recordings for frequencies above 32 kHz.
• Analyze the fraction of responsive single-unit and multi-unit cells in the cochlear nucleus versus inferior colliculus for ultrasonic vocalizations.
• Investigate the relationship between auditory brainstem response measurements and single-unit activity patterns across the auditory pathway.
• Model the specialization for high-frequency processing by correlating neural responses from the periphery and midbrain to tone and vocalization stimuli.

Strengths

• Includes neural recordings from three distinct anatomical stages of the auditory pathway: auditory nerve, cochlear nucleus, and inferior colliculus.
• Focuses on a specific auditory processing question regarding high ultrasonic frequencies above 32 kHz relevant to mouse vocalizations.
• Data is associated with a peer-reviewed research publication, providing methodological context.
• Released under a permissive CC0 1.0 public domain license for broad reuse.

Limitations

• The specific sample size (number of recordings, animals, or cells) is not provided in the available metadata.
• Data structure, file formats, and column definitions are unknown, requiring significant exploration before analysis.
• As a 2020 snapshot from a specific study, the dataset may not be updated or expanded.

Provenance

Source

Dryad digital repository.

Collection Method

Laboratory measurements of evoked potentials, single-unit, and multi-unit neural responses to tones and vocalizations in mice.

Freshness

Last updated 2020-06-24.