Hippocampal CA1 Neuron Firing and Theta Activity in Rat Pups (P17-26)

Featuring electrophysiological recordings of hippocampal CA1 single neuron firing and theta activity from rat pups across three developmental stages (P17-19, P21-23, and P24-26). Collected by Jangjin Kim and published in 2020, the data tracks neural responses during six sessions of associative learning using tone and periorbital stimulation.

Use Cases

• Analyzing age-dependent changes in spike/theta phase-locking during the tone conditioned stimulus (CS)
• Comparing theta power changes (4–10 Hz) and theta/delta ratios across the three postnatal age groups
• Modeling CA1 pyramidal cell task-related activity during CS-US paired training sessions

Strengths

• Includes three distinct developmental age groups (P17-19, P21-23, P24-26)
• Captures both single-unit pyramidal cell activity and local field potential theta oscillations
• Standardized associative learning protocol using six controlled training sessions

Limitations

• Small sample size typical of invasive electrophysiology studies
• Geographically limited to the dorsal hippocampal CA1 area
• Temporal scope restricted to the early postnatal period

Provenance

Source

Dryad Digital Repository

Collection Method

In vivo electrophysiological recording using sensors during associative learning tasks

Freshness

Last updated 2020-06-24; static research data.