Hippocampal Single Unit Recordings in MAM Model Rats

Encompassing in vivo single unit recordings from the hippocampal CA1 region of freely moving rats. The data was collected to study how environmental enrichment impacts fine spike timing and place-modulated rate coding in a model of cortical malformations. The dataset was authored by Amanda E. Hernan and last updated in June 2020.

Use Cases

• Analyze fine spike timing (FST) parameters to assess the effects of environmental enrichment on neural coding.
• Model the relationship between FST characteristics and spatial coherence of hippocampal place cells.
• Compare place-modulated rate coding in control, MAM-treated, and environmentally enriched rat cohorts.
• Investigate how generalized linear modeling-extracted FST parameters predict spatial cognition surrogates.

Strengths

• Data is derived from in vivo recordings in freely moving animals, providing ecologically relevant neural activity.
• The study design includes control, MAM-treated, and environmentally enriched groups for comparative analysis.
• Data is associated with a published research article on a specific neurodevelopmental model.
• Released under a permissive CC0 1.0 public domain license.

Limitations

• The specific number of recordings, rows, or sample size is not provided in the input.
• Data format and structure (e.g., column names, file types) are unknown, which may complicate initial analysis.
• The dataset is focused on a specific animal model (MAM-treated rats), limiting direct generalizability to other conditions.

Provenance

Source

Dryad digital repository.

Collection Method

Hippocampal in vivo single unit recordings performed in freely moving animals in an open arena.

Freshness

Last updated on 2020-06-24.