Inappropriate Tumor Marker Requests in Shanghai Pulmonary Patients 2014-2015

2706 patients with chronic obstructive pulmonary disease (COPD) or primary lung cancer (PLC) from three Shanghai hospitals were studied. The retrospective analysis quantified inappropriate tumor marker (TM) requests, finding 58.27–79.06% of 12,496–16,956 requests were unsuitable, costing 650,200–1,014,156 yuan. The dataset supports analysis of TM overuse, associated costs, and guideline adherence in pulmonary care.

Use Cases

• Analyze the proportion of inappropriate TM requests (58.27–79.06%) across patient groups like COPD and PLC to identify patterns of overuse.
• Calculate the financial impact of inappropriate TM use by examining costs (650,200–1,014,156 yuan) relative to total hospitalization and examination expenses.
• Evaluate the clinical and cost-effectiveness of specific TM panels (e.g., CEA+CYFRA211+SCC+NSE) using metrics like the reported ROC curve area of 0.813.
• Study the distribution of TM requests and associated costs across different hospital departments (respiratory, thoracic surgery, oncology).

Strengths

• Contains data from 2706 patient records, providing a substantial clinical sample.
• Quantifies inappropriate use with specific percentages (58.27–79.06%) and monetary costs (650,200–1,014,156 yuan).
• Includes a validated clinical effectiveness metric, reporting an ROC curve area of 0.813 for a specific TM panel.
• Data is sourced from a multi-center study across three hospitals, enhancing generalizability within the Shanghai context.

Limitations

• Data is from 2014-2015 and may not reflect current clinical practices or healthcare policies.
• Study is limited to three hospitals in Shanghai, China, limiting geographic and healthcare system generalizability.
• The raw dataset structure (columns, rows) is unknown, which may complicate direct analysis without further metadata.

Provenance

Source

Dryad, authored by Haichen Zhang.

Collection Method

Retrospective study of hospital records.

Time Range

2014 to 2015.

Freshness

Last updated 2020-06-24; data covers 2014-2015.

Geography

Three hospitals in Shanghai, China.