Xenopus Metamorphosis Neuromuscular Development Data

Featuring research data on spinal neuron and hindlimb muscle development during early metamorphosis in Xenopus. It examines the expression of Islet1/2, choline acetyltransferase, vesicular acetylcholine transporter, and glutamate receptors. The dataset is associated with a study demonstrating a transient, non-cholinergic neuromuscular signaling phase.

Use Cases

• Analyze the temporal expression patterns of Islet1/2, choline acetyltransferase, and vesicular acetylcholine transporter in labeled spinal neurons.
• Investigate the co-occurrence of glutamate receptor expression in hindlimb muscles with nicotinic antagonist-resistant neuromuscular activity.
• Model the developmental switch from glutamate-sensitive to cholinergic transmitter signaling at neuromuscular synapses.

Strengths

• Data is derived from a controlled experimental study on Xenopus metamorphosis.
• Includes analysis of specific molecular markers like Islet1/2, choline acetyltransferase, and glutamate receptors.
• Associated with peer-reviewed research published in 2020.

Limitations

• The dataset size, row count, and specific file formats are unknown.
• Data is highly specialized for a specific biological model and developmental stage.
• Sample data and column structure are not provided for immediate analysis.

Provenance

Source

Dryad digital repository

Collection Method

Experimental data from electrophysiological recordings and molecular labeling in Xenopus laevis.

Time Range

Covers the early metamorphosis period in Xenopus development.

Freshness

2020-06-24