Human Opioidergic Hedonic Processing Data from fMRI Study

Featuring fMRI data from a within-subject pharmacological challenge study investigating opioidergic mechanisms in hedonic processing. The study used the opioid receptor antagonist naloxone to measure its effect on neural activation in regions like the ventral striatum and amygdala during reward delivery versus anticipation. The dataset was authored by Christian Buchel and last updated in June 2020.

Use Cases

• Analyze naloxone-induced activation changes in the ventral striatum and amygdala during reward delivery.
• Compare fMRI signal patterns between erotic picture viewing and monetary symbol viewing under pharmacological challenge.
• Investigate the dissociation between reward delivery and reward anticipation phases in the lateral orbitofrontal cortex and medial prefrontal cortex.

Strengths

• Data originates from a controlled within-subject pharmacological challenge design with naloxone.
• fMRI measurements target specific brain regions including the hypothalamus, nucleus accumbens, and amygdala.
• Dataset is published under a CC0 1.0 public domain license, allowing unrestricted reuse.

Limitations

• The specific sample size (number of subjects or scan sessions) is not provided in the input.
• The available data fields, column structure, and file formats are unknown.
• The dataset's temporal coverage and geographic origin of participants are not specified.

Provenance

Source

dryad

Collection Method

Within-subject pharmacological challenge design with naloxone and fMRI.

Freshness

Last updated on 2020-06-24.