HCMV Serology and Health Data from a Rural Ugandan Cohort

Serum samples from 2,174 Ugandan individuals were investigated for HCMV antibodies, with data linked to demographic information, co-infections, and cardiovascular disease measurements. The dataset provides insights into HCMV epidemiology, showing 83% seropositivity by age one and 95% by age five. It was created by Lisa Stockdale and published in 2020.

Use Cases

• Analyze HCMV IgG levels across demographic groups like female sex and HIV status to identify risk factors.
• Investigate the association between active pulmonary tuberculosis (TB) status and elevated HCMV antibody levels.
• Examine the relationship between HCMV seropositivity and cardiovascular disease (CVD) risk factor measurements.
• Model HCMV seroprevalence trends by age using data from a cohort with known seropositivity rates.

Strengths

• Contains data from 2,174 individuals, providing a substantial sample size for analysis.
• Reports specific HCMV seropositivity rates: 83% by age one and 95% by age five.
• Links HCMV serology to multiple health variables including demographic, co-infection, and CVD measurement data.

Limitations

• The dataset is cross-sectional, limiting causal inference for observed associations.
• Focus is on a specific rural Ugandan cohort, which may limit generalizability to other populations.
• The specific column structure, file formats, and row count for tabular data are unknown.

Provenance

Source

Lisa Stockdale via Dryad.

Collection Method

Serum samples from Ugandan individuals were investigated for HCMV antibodies and linked to other health data.

Freshness

Last updated in June 2020.

Geography

Rural Uganda.