A dataset from Borealis Harvested Dataverse by Sarah Neuman, last updated April 25, 2026. It contains data from a study dissecting the mechanisms targeting the bridge-like lipid transfer protein BLTP2 (hobbit) to endoplasmic reticulum-plasma membrane contact sites in Drosophila. The research identifies a conserved adapter protein, bilbobaggins (bbo), and cis-acting sequences in Hobbit's C-terminal tail as key regulators.
Use Cases
- Modeling protein targeting mechanisms based on the described 'hook and latch' paradigm.
- Analyzing genetic interactions between hobbit and bbo based on the described phenocopy.
- Studying structure-function relationships in lipid transfer proteins based on the described cis-acting sequences.
Strengths
- Data is associated with a peer-reviewed scientific study, as indicated by the abstract format.
- The dataset description provides a specific biological model (Drosophila) and protein targets (BLTP2/hobbit, bbo).
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Last updated 2026-04-25 04:15:42; freshness should be verified.
Provenance
- Source
- Borealis Harvested Dataverse
- Collection Method
- Likely contains experimental data from the described cell biology study.
- Freshness
- Last updated 2026-04-25 04:15:42.