V1 Membrane Potential Dynamics in Awake Mice with PV and PYR Recordings

Targeted patch-clamp recordings and synchronous local field potentials (LFPs) from PV and PYR neurons in the V1 cortex of awake mice. This 2020 dataset by Quentin Perrenoud captures subthreshold membrane potential dynamics during spontaneous and visually evoked gamma activity (30–80 Hz).

Use Cases

• Quantifying phase-locking of PV and PYR firing to LFP gamma cycles
• Analyzing subthreshold membrane potential (Vm) fluctuations during 30–80 Hz oscillations
• Comparing synaptic activity patterns between spontaneous and visually evoked neural states

Strengths

• Targeted patch-clamp recordings from specific PV and PYR cell types
• Synchronous LFP and intracellular membrane potential data
• Covers both spontaneous and visually evoked gamma oscillations (30–80 Hz)

Limitations

• Small sample size inherent to intracellular recording techniques
• Geographically limited to layer 2/3 of the mouse V1 cortex
• Specific column headers and file counts are not detailed in the metadata

Provenance

Source

Quentin Perrenoud via Dryad

Collection Method

Targeted patch-clamp recordings and LFP sensors in awake mice

Freshness

Last updated June 2020; static research dataset.