MNI-HISUB25: Submillimetric 3T MRI and Hippocampal Labels for 25 Subjects

Supplying submillimetric T1- and T2-weighted MRI scans and manual hippocampal subfield labels for 25 healthy subjects. Developed by Jessie Kulaga-Yoskovitz and released in 2020, the collection includes stereotaxic probabilistic anatomical maps and detailed sequence information. The data focuses on three specific subregions: the subicular complex, CA1-3, and CA4-DG.

Use Cases

• Training segmentation algorithms for the subicular complex and CA1-3 subfields
• Validating automated hippocampal segmentation tools against manual labels
• Analyzing mesiotemporal anatomy using the provided stereotaxic probabilistic maps

Strengths

• Submillimetric resolution MRI scans
• High inter-rater reliability with Dice indices ≥87%
• Includes both T1- and T2-weighted contrasts for 25 subjects

Limitations

• Small sample size of 25 subjects
• Limited to healthy individuals, excluding pathological variations
• Manual segmentation is restricted to three broad subregions rather than finer subfields

Provenance

Source

Jessie Kulaga-Yoskovitz, Dryad

Collection Method

3-Tesla MRI scanning with manual expert annotation

Freshness

Last updated June 2020; static dataset.