Saccharomyces cerevisiae Diauxic Lag Growth Curves Across Natural Isolates

Data from a study on natural variation in microbial growth strategies during nutrient transitions. The dataset includes measurements from natural isolates of Saccharomyces cerevisiae grown in glucose-galactose mixtures, analyzing the tradeoff between preparation for nutrient depletion and growth cost. It contains experimental results on diauxic lag, GAL gene expression, and growth curves.

Use Cases

• Analyze the correlation between GAL gene expression levels prior to glucose exhaustion and the duration of the diauxic lag across different strains.
• Model the cost-benefit tradeoff by comparing upfront growth costs against competitive advantages post-glucose depletion using growth curve data.
• Compare the steady-state response of GAL genes to glucose-galactose mixtures versus induction kinetics as determinants of preparation extent.

Strengths

• Data originates from a peer-reviewed study published in PLOS Biology, ensuring scientific rigor.
• Examines multiple natural isolates of Saccharomyces cerevisiae, capturing biological diversity.
• Includes measurements of both physiological (growth curves, optical density) and molecular (GAL gene expression) phenotypes.

Limitations

• Specific sample size, row count, and column structure are not provided in the input.
• Data is limited to laboratory growth conditions in defined sugar mixtures, which may not fully reflect natural environmental complexity.
• The dataset is static from a single study, with no indication of planned updates or expansions.

Provenance

Source

Dryad digital repository.

Collection Method

Experimental measurements from microbial physiology studies, including fluorescent reporter assays and growth curve analysis.

Freshness

Last updated in June 2020.