Modified Rankin Scale and 5-Year Stroke Outcomes in Oxford Cohort

2002-2014 data from 1,607 consecutive ischemic stroke patients in the Oxford Vascular Study, a population-based prospective cohort. The dataset relates 3-month modified Rankin Scale (mRS) scores to 1-year and 5-year disability, mortality, and health/social-care costs, with analysis of trial ineligibility based on pre-morbid mRS.

Use Cases

• Compare ordinal versus dichotomized (0-1/2-6 or 0-2/3-6) representations of the 3-month mRS for predicting 5-year mortality and disability.
• Model 5-year health and social care costs using 3-month mRS scores, adjusted for age and sex.
• Analyze the proportion of patients with pre-morbid mRS >1 or >2 to assess potential exclusion rates for clinical trials using dichotomous outcomes.
• Investigate associations between pre-morbid mRS and factors like female sex, socio-economic deprivation, and age among 3-month survivors.

Strengths

• Contains data from 1,607 ischemic stroke patients, providing a substantial clinical cohort.
• Includes long-term follow-up for outcomes and costs at 1-year and 5-year intervals.
• Data originates from the Oxford Vascular Study, a well-defined population-based prospective cohort study.

Limitations

• Sample is limited to ischemic stroke patients from a single study region (Oxford, UK), limiting generalizability.
• Specific column definitions and raw data structure are not provided in the input.
• Data collection ended in 2014, so findings may not reflect current treatment protocols.

Provenance

Source

Oxford Vascular Study, a population-based prospective cohort study.

Collection Method

Clinical data from consecutive ischemic stroke patients enrolled between 2002 and 2014.

Time Range

2002-2014

Freshness

Last updated 2020-06-24; data covers 2002-2014.

Geography

Oxford region, United Kingdom.