Phosphate Levels and Clinical Outcomes in 1,144 Acute Kidney Injury Patients

1,144 patients with acute kidney injury undergoing continuous renal replacement therapy (CRRT) were observed between January 2009 and September 2016. The dataset includes clinical parameters such as phosphate levels, APACHE II and SOFA scores, mean arterial pressure, and urine output, used to assess disease severity and mortality risk. It was created by Su-Young J Jung to investigate phosphate as a biomarker for adverse outcomes.

Use Cases

• Model 28-day and 90-day mortality risk using phosphate levels, APACHE II score, and Charlson comorbidity index from 1,144 patient records.
• Analyze the correlation between phosphate levels at CRRT initiation and disease severity metrics like SOFA score and mean arterial pressure.
• Investigate the predictive value of 24-hour phosphate level changes on patient survival outcomes in critically ill cohorts.

Strengths

• Contains 1,144 patient records with a mean age of 63.2 years and 61.6% male representation.
• Includes multiple validated clinical severity scores (APACHE II, SOFA) and physiological measurements (mean arterial pressure, urine output).
• Data collection spans over 7 years (January 2009 to September 2016), providing a substantial observational period.

Limitations

• Observational study design limits causal inference regarding phosphate levels and mortality.
• Patient population is specific to those receiving CRRT in an ICU setting, limiting generalizability to other AKI patients.
• Specific column definitions, data formats, and the presence of missing values are not detailed in the available description.

Provenance

Source

Dryad digital repository.

Collection Method

Observational study of patients with AKI receiving continuous renal replacement therapy.

Time Range

January 2009 to September 2016.

Freshness

Data covers up to September 2016, with metadata last updated in June 2020.