Rat Wound Healing Data Comparing Polypropylene and Calcium Alginate Prostheses

Polypropylene-treated wounds exhibited greater area reduction compared to calcium alginate in a paired full-thickness excisional model using Wistar rats. Data includes wound area measurements, histological features, and oxidative stress markers assessed at 3, 7, and 14 days. Author Kinulpe Sampaio published the 17.1 KB dataset on figshare in 2026 under a CC-BY-4.0 license.

Use Cases

• Compare wound healing efficacy between polypropylene and calcium alginate prostheses based on wound area reduction data.
• Analyze the relationship between oxidative stress markers and tissue organization based on histological and biochemical measurements.
• Model the time-course of secondary-intention wound healing based on measurements taken at 3, 7, and 14 days.
• Investigate within-subject treatment effects using the paired wound model described.

Strengths

• Data enables within-subject comparisons from a paired wound model in Wistar rats.
• Includes multiple measurement types: wound area, histological features, and oxidative stress markers.
• Effect sizes for treatment comparisons are described as moderate to large across timepoints.
• Dataset is openly licensed under CC-BY-4.0.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a rodent model; the description notes translation to humans requires caution.

Provenance

Source

figshare

Collection Method

Experimental study evaluating calcium alginate and polypropylene prosthesis effects using a paired full-thickness excisional wound model in Wistar rats.

Freshness

Last updated 2026-04-20 20:40:16; freshness should be verified.