Drosophila buzzatii Esterase-2 Allele Fitness and Frequency Data

Data from J. Stuart F. Barker's 2020 Dryad publication investigates selection at the Esterase-2 locus in Drosophila buzzatii. It includes results from perturbation-reperturbation experiments on 20 replicate cage populations and pre-adult viability estimates from crosses among 12 sequential gel electrophoretic alleles. The experiments test for direct selective effects versus linked loci influences.

Use Cases

• Analyze allele frequency change patterns across 20 replicate cage populations to test for selection versus drift.
• Model relative viability fitnesses using pre-adult viability estimates from crosses among 12 sequential gel alleles.
• Investigate gene interactions and epistasis by examining deviations in four populations that dissipated linkage disequilibrium.

Strengths

• Data supports a specific genetic hypothesis with results from 20 replicate laboratory populations.
• Includes pre-adult viability estimates derived from crosses among 12 distinct sequential gel electrophoretic alleles.
• Published under a permissive CC0 1.0 license, facilitating reuse and analysis.

Limitations

• The dataset's underlying structure, including row count, column names, and file formats, is unspecified.
• Data is derived from controlled laboratory cage experiments, limiting direct extrapolation to natural field conditions.
• Focus is on a single species and locus, reducing generalizability to other genetic systems.

Provenance

Source

Dryad digital repository.

Collection Method

Laboratory perturbation-reperturbation cage experiments and sequential gel electrophoresis for allele identification.

Freshness

Last updated on 2020-06-24.