PERSPIRE Study: 1-Minute Sit-to-Stand Test Data for Pulmonary Hypertension

Data from the PERSPIRE study evaluates the safety and utility of the 1-minute sit-to-stand test for remote risk assessment in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. The dataset includes results from 75 patients who performed both the 1-minute sit-to-stand and Incremental Shuttle Walk tests, with physiological parameters like heart rate, WHO FC, emPHAsis-10, and NT-proBNP. The data was published by Carol Keen on figshare under a CC-BY-4.0 license and was last updated on 2026-05-28.

Use Cases

• Compare physiological responses between the 1-minute sit-to-stand and Incremental Shuttle Walk tests based on heart rate, WHO FC, emPHAsis-10, and NT-proBNP data.
• Assess the safety profile of sub-maximal exercise tests for pulmonary hypertension patients in a hospital setting.
• Investigate patient willingness for remote/home-based exercise testing as indicated by the 97% willingness rate.
• Analyze correlations between different exercise metrics and established risk assessment parameters for pulmonary hypertension.

Strengths

• Includes data from 75 patients (60 with pulmonary arterial hypertension, 15 with chronic thromboembolic pulmonary hypertension).
• Reports specific physiological changes, such as a +9.4 bpm heart rate increase for the sit-to-stand test versus +38.3 bpm for the shuttle walk test.
• Provides statistical correlations (p-values) for multiple metrics including WHO FC, emPHAsis-10, and NT-proBNP.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 46.6 KB, indicating limited scope.

Provenance

Source

Carol Keen via figshare.

Collection Method

Prospective cohort study where patients performed two exercise tests on the same day.

Freshness

Last updated 2026-05-28 17:26:52; freshness should be verified.