Mouse Lateral Geniculate Nucleus Neuron Receptive Field Properties

Electrophysiological recordings from mouse LGN neurons under visual stimulation paradigms. The data includes properties such as centre-surround organization, receptive field size, spontaneous firing rate, and linearity of spatial summation. It also captures temporal frequency tuning features like 'high-pass' and 'low-pass' cells, contrast gain, and a small proportion of direction/orientation selective cells.

Use Cases

• Analyze the relationship between cell location (anterior/middle/posterior LGN) and response properties like ON/OFF classification or linearity.
• Model contrast sensitivity and temporal frequency tuning properties to compare ON-cells and OFF-cells.
• Investigate the prevalence and characteristics of direction/orientation selectivity within the recorded neuron population.
• Examine the correlation between receptive field size and other measured properties such as spontaneous firing rate.

Strengths

• Data includes multiple response properties per neuron: centre-surround organization, receptive field size, spontaneous firing rate, and linearity.
• Neurons are localized within a 3-D LGN volume model, categorizing them into anterior, middle, or posterior regions.
• Study reveals specific temporal frequency tuning features ('high-pass'/'low-pass') and contrast gain measurements.

Limitations

• The sample includes only a small proportion of cells exhibiting direction/orientation selectivity, limiting statistical power for analyzing these features.
• Data is specific to the mouse LGN, which may limit direct applicability to studies of higher-order mammals like primates.
• The exact number of recorded neurons (rows) and measured variables (columns) is not specified in the provided input.

Provenance

Source

Dryad digital repository, authored by Jiaying Tang.

Collection Method

Recordings from mouse LGN neurons using multisite-electrode-arrays (MEAs) under visual stimulation paradigms.

Freshness

Data was last updated in June 2020.