Metabolomic Profiles of Holotrichia serrata Larvae Infected by Metarhizium anisopliae

Metabolomic profiling revealed distinct and reproducible separation between infected and control larvae, with principal component analysis explaining 94.66% of total variance. A core set of 119 metabolites was consistently altered across all infection replicates, indicating a robust and conserved metabolic response to fungal challenge. The dataset, authored by Himanshu Kumar and last updated in May 2026, is available under a CC-BY-4.0 license.

Use Cases

• Identify metabolic biomarkers of fungal infection based on the 119 consistently altered metabolites.
• Analyze shifts in primary metabolism based on the marked depletion of amino acids like proline and tryptophan.
• Investigate secondary metabolite production based on the upregulation of alkaloids, phenolics, and nitrogen-containing compounds.
• Validate statistical models for metabolomic separation based on the PCA explaining 94.66% of variance.

Strengths

• Principal component analysis explains 94.66% of total variance, indicating strong separation.
• A core set of 119 metabolites was consistently altered across all infection replicates.
• The description provides specific examples of altered metabolites (e.g., proline, tryptophan).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small at 788.4 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Metabolomic profiling via LC-MS.

Freshness

Last updated 2026-05-15 06:33:58; freshness should be verified.