Goji Berry vs. Chlorhexidine Mouthwash Clinical Trial for Chronic Periodontitis

A randomized clinical trial with 57 adult participants compared the efficacy of Lycium barbarum (goji berry) mouthwash to 0.2% chlorhexidine gluconate for managing chronic periodontitis. The dataset likely contains measurements of gingival index, plaque index, bleeding on probing, clinical attachment loss, probing pocket depth, microbial load, and antioxidant protein thiol levels in saliva at baseline, 15 days, and one month. The study was authored by Aditi Chopra and is available via the paperswithcode platform.

Use Cases

• Compare the clinical efficacy of a plant-based mouthwash to a conventional antiseptic based on gingival and plaque index scores.
• Analyze changes in microbial load and antioxidant levels in saliva over a one-month treatment period.
• Investigate correlations between clinical parameters like probing pocket depth and biochemical markers like protein thiols.
• Train predictive models for periodontal disease management outcomes using clinical trial data.

Strengths

• Data originates from a structured randomized clinical trial with 57 participants (29 males, 28 females).
• Includes multiple clinical and biochemical outcome measures collected at three time points.
• The study design allows for direct comparison between a novel plant-based treatment and a standard antiseptic.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.
• Data may reflect the specific population and conditions of a single clinical trial.

Provenance

Source

paperswithcode

Collection Method

Randomized clinical trial data collection.