Genomic Atlas of Gut Clostridia: Phylogeny and Butyrate/Propionate Production

Laura Sola's dataset provides a genomic reclassification of 1,897 intestinal Clostridia species from the Unified Human Gastrointestinal Genome database. The analysis identifies 519 potential butyrate producers, 257 propionate producers, and 77 capable of producing both, based on whole-genome phylogeny and pathway analysis. The dataset was last updated on April 10, 2026.

Use Cases

• Phylogenetic analysis of gut Clostridia based on the reclassification of 1,897 species into genera and families.
• Identifying potential butyrate and propionate producers based on the presence of biosynthetic pathway enzymes.
• Assessing the relative abundance of butyrate-producing species in healthy human microbiomes based on the profiling of 151 faecal metagenomes.

Strengths

• Contains genomic data for 1,897 Clostridia species, including 404 with recognized taxonomy.
• Pathway analysis identifies 519 potential butyrate producers and 257 potential propionate producers.
• Includes abundance data from 151 faecal metagenomes of healthy subjects.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare, author Laura Sola.

Collection Method

Genomes retrieved and reclassified using GTDB-Tk; phylogeny determined from 120 ubiquitous single-copy proteins; metabolic pathways investigated with GapSeq.

Time Range

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Freshness

Last updated 2026-04-10 05:59:11; freshness should be verified.

Geography

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