HIV Cognitive Impairment and Treatment Response from Multimodal Neuroimaging

Data Sheet 1_A multimodal imaging–based integrative framework for HIV-associated cognitive impairment and treatment response.pdf is a 256.6 KB PDF file authored by Xing Qiu and last updated on 2026-04 13. The dataset describes a study applying a multimodal integrative model to associate baseline MR neuroimaging metrics with cognitive performance and its change over 12 weeks of combination antiretroviral therapy in persons with HIV.

Use Cases

• Modeling short-term cognitive trajectories based on multimodal neuroimaging features like volumetric data and cerebral blood flow.
• Identifying brain region predictors for cognitive change based on features from cortical, subcortical, and white matter regions.
• Comparing multimodal versus unimodal model performance for explaining longitudinal outcomes in medical data.
• Developing interpretable statistical frameworks for 'large p, small n' datasets in clinical neuroscience.

Strengths

• Dataset is associated with a detailed methodological description of a multimodal integrative model.
• The study design includes longitudinal data over a 12-week treatment period.
• The data file is openly available under a CC-BY-4.0 license.

Limitations

• The dataset is a 256.6 KB PDF, which suggests it contains summary or descriptive data rather than raw data tables.
• Column-level documentation and sample data are unavailable, requiring manual inspection after download.
• Row count and the specific structure of the underlying data are unknown.

Provenance

Source

figshare, author Xing Qiu

Collection Method

Data appears to be derived from a clinical study applying multimodal MR neuroimaging (volumetric, cerebral blood flow, cerebrovascular reactivity, diffusion MRI).

Time Range

Study includes longitudinal changes over 12 weeks of treatment.

Freshness

Last updated 2026-04-13 05:47:48

Geography

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