Network Meta-Analysis of Aerobic Exercise Effects on Bone Density in Osteoporosis Patients

27 randomized controlled trials involving 2,183 participants were analyzed to compare the effects of different aerobic exercise prescriptions on bone mineral density. The meta-analysis, conducted by Xiaobin Zhou and uploaded to figshare in June 2026, followed PRISMA guidelines and used Stata 15.0 software. Results identified optimal exercise parameters: high intensity, 30-59 minutes per session, 4–5 times per week, over 24 weeks.

Use Cases

• Designing optimal aerobic exercise protocols for osteoporosis patients based on analyzed intensity, duration, and frequency parameters.
• Comparing the efficacy of different exercise intensities (high, medium, low-to-medium) for improving bone mineral density.
• Informing clinical guidelines on exercise prescription duration and weekly frequency for bone health.
• Prioritizing intervention strategies using Surface Under the Cumulative Ranking Curve (SUCRA) rankings derived from the analysis.

Strengths

• Analysis is based on 27 randomized controlled trials, a substantial evidence base.
• The study followed PRISMA guidelines and used Cochrane bias risk assessment, suggesting a structured methodological approach.
• Results provide specific, ranked recommendations for exercise intensity, session duration, weekly frequency, and intervention length.

Limitations

• The primary data file is a 16.3 MB DOCX document; the underlying tabular data used for the meta-analysis is not directly available in a structured format.
• Row count and column-level documentation for the source trial data are unknown, limiting reproducibility and direct analysis.
• Geographic and demographic coverage of the included studies is not specified, which may limit generalizability.

Provenance

Source

Xiaobin Zhou

Collection Method

Systematic review and network meta-analysis of literature from 7 databases including PubMed, Web of Science, and Cochrane Library.

Time Range

Literature searched from database inception to June 2025.

Freshness

Last updated 2026-06-03 04:26:43