ADAMTS2 in Prostate Cancer: Bioinformatic and Experimental Analysis

A research document analyzing the role of ADAMTS2 in prostate cancer progression. The analysis integrates bioinformatic data from TCGA-PRAD with in vitro and in vivo experimental validation. The document was authored by Jinzhuo Ning and last updated in April 2026.

Use Cases

• Study gene expression correlations with clinical outcomes based on TCGA-PRAD data mentioned in the description
• Investigate molecular pathways involving ADAMTS2, COL1A1, and FAK/PI3K/AKT signaling
• Explore mechanisms of ferroptosis resistance in cancer cells based on SLC7A11 and GPX4 expression

Strengths

• Analysis integrates multiple data sources, including TCGA-PRAD clinical data and experimental validation
• Document is 887.2 KB, providing a detailed methodological and results narrative
• Released under a CC-BY-4.0 license, allowing for broad reuse

Limitations

• The primary data file is a DOCX document, not a structured dataset; column-level documentation is absent
• Row count for any underlying data is unknown, which may limit suitability assessment
• Freshness should be verified as the last update date is in the future (2026-04-27)

Provenance

Source

figshare

Collection Method

Integrated bioinformatic analysis of TCGA-PRAD data with clinical specimen validation and in vitro/in vivo experiments.

Freshness

Last updated 2026-04-27 04:11:49