ADGRD1 in Bladder Cancer: Gene Expression and Clinical Prognosis Analysis

A research paper analyzing the role of the ADGRD1 gene in bladder cancer progression and angiogenesis. The study uses GEPIA3 datasets for clinical significance and includes in vitro and in vivo functional assays. The work was authored by Chen Li and last updated on 2026-05-28.

Use Cases

• Identify prognostic biomarkers for bladder cancer based on ADGRD1 expression levels mentioned in the description.
• Study the relationship between gene expression and clinical stage or survival outcomes using the referenced GEPIA3 datasets.
• Investigate the PI3K/AKT/mTOR signaling pathway's role in tumor angiogenesis as described in the mechanistic findings.
• Validate in vitro and in vivo findings on cell proliferation, migration, and endothelial tube formation from the described functional assays.

Strengths

• The dataset is associated with a specific, detailed research study on a defined molecular target (ADGRD1).
• Includes analysis of clinical significance using established bioinformatics datasets (GEPIA3).
• Mechanistic validation involves pharmacological inhibitors and activators (SC79, LY294002) as described.

Limitations

• The primary data file is a 770.7 KB PDF, which likely contains summarized results rather than raw, reusable datasets.
• Column-level documentation and sample data are unavailable, limiting immediate analysis.
• Row count and the structure of any underlying tabular data are unknown.

Provenance

Source

figshare

Collection Method

Analysis of public bioinformatics datasets (GEPIA3) and original experimental research including cell line assays and xenograft models.

Freshness

Last updated 2026-05-28 04:53:04.