Meta-Analysis on Adverse Childhood Experiences and Non-Suicidal Self-Injury Risk

Qian He's meta-analysis, last updated April 2026, synthesizes evidence from 13 observational studies on the association between Adverse Childhood Experiences (ACEs) and Non-Suicidal Self-Injury (NSSI). The analysis pools effect sizes using a random-effects model, reporting odds ratios for specific ACE types like physical, sexual, and emotional abuse. The dataset is a 1.1 MB document containing the full study methodology, results, and conclusions.

Use Cases

• Quantifying the association strength between specific ACE types and NSSI risk based on reported odds ratios.
• Informing clinical screening protocols based on the cumulative risk findings for individuals with multiple ACEs.
• Supporting systematic review methodology by examining the search strategy and quality assessment process described.

Strengths

• Includes specific pooled odds ratios and confidence intervals for multiple ACE categories, such as physical abuse (OR=2.38) and cumulative exposure (ACEs≥3, OR=6.13).
• Provides a detailed methodological description, including the search databases, statistical model (random-effects), and analysis software (Stata 15).
• Registered as a systematic review with a PROSPERO identifier (CRD42026128495), indicating a structured protocol.

Limitations

• The underlying data (rows, columns) from the 13 included studies is not provided, limiting direct analysis.
• The 1.1 MB file size suggests the dataset is a summary document rather than a raw data repository.
• Column-level documentation is absent; field semantics must be inferred from the text after download.

Provenance

Source

Qian He via figshare.

Collection Method

Systematic review and meta-analysis of observational studies from PubMed, Embase, Web of Science, and Cochrane Library.

Time Range

Literature search covered from database inception to 30 November 2025.

Freshness

Last updated 2026-04-13 05:36:00.

Geography

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