Mouse Study on Glycemic Control and Inflammation from Olive Oil vs. Coconut Oil Diets

A 5-month study on male C57BL/6N mice fed high-fat diets based on extra virgin olive oil or coconut oil. The dataset, authored by Lena Keller and shared under CC-BY-4.0, includes results from glucose, insulin, and pyruvate tolerance tests, flow cytometry of immune cells, and analyses of metabolic partitioning. The associated PDF file is 3.4 MB in size.

Use Cases

• Compare glucose intolerance development based on results from glucose tolerance tests mentioned in the description
• Analyze tissue-specific inflammatory responses based on flow cytometry data from adipose tissue, colon, and liver
• Investigate metabolic partitioning between fatty acid storage and utilization based on hepatic lipid accumulation and circulating metabolite levels
• Study the relationship between diet, gut microbiota, and systemic inflammation as described in the results

Strengths

• Study duration of up to 5 months provides longitudinal metabolic data
• Multiple experimental endpoints including tolerance tests, flow cytometry, and metabolic analyses are described
• Clear comparison of two distinct high-fat diets (olive oil vs. coconut oil) matched for macronutrients

Limitations

• Dataset consists of a single 3.4 MB PDF file; underlying raw data tables are not directly accessible
• Row count and column-level documentation are unknown, requiring manual inspection after download
• Data is specific to a male C57BL/6N mouse model, which may limit generalizability

Provenance

Source

figshare

Collection Method

Experimental study involving dietary intervention, metabolic tests, and tissue analysis in mice.

Time Range

Study duration of up to 5 months.

Freshness

Last updated 2026-04-28 15:06:16; freshness should be verified