Msr-Antioxidase-Host Gene Circuit Data for Legume-Rhizobium Symbiosis

A 2026 research article published on figshare details the role of methionine sulfoxide reductases (Msrs) in the symbiotic nitrogen fixation between Mesorhizobium huakuii 7653R and Astragalus sinicus. The study by Zaiyong Si includes expression profiling, phenotypic analyses of bacterial mutants, and symbiotic assays measuring nodulation and nitrogen fixation efficiency. The data likely contains gene expression patterns, physiological trait measurements, and host gene transcription levels related to oxidative stress and symbiosis.

Use Cases

• Modeling redox regulatory networks based on described protein-protein interactions between Msrs and chaperones/antioxidant enzymes.
• Analyzing gene expression patterns of msr genes during different symbiotic stages mentioned in the description.
• Studying the impact of oxidative stress on bacterial physiology based on described traits like motility, biofilm formation, and enzyme activities.
• Investigating host-symbiont crosstalk based on described regulation of host antioxidant and symbiotic-related genes.

Strengths

• Includes data from systematic characterization of four specific Msr genes (MsrA1, MsrB1, MsrA2, MsrB2).
• Phenotypic analyses cover multiple bacterial traits: motility, biofilm formation, and antioxidant enzyme activities.
• Symbiotic assays provide measures of nodule number and nitrogen fixation efficiency.

Limitations

• The primary data format is a PDF (2.7 MB), which may require extraction to access structured data.
• Row count and column-level documentation are unknown, limiting suitability assessment.
• Data may reflect the specific experimental conditions and model system (M. huakuii 7653R and A. sinicus) used in the study.

Provenance

Source

Zaiyong Si via figshare.

Collection Method

Experimental research involving sequence analysis, expression profiling, mutant construction, phenotypic assays, and symbiotic tests.

Freshness

Last updated 2026-06-03.