T Cell Receptor Germline Gene Annotations for Pinnipeds and Comparative Species

A systematic annotation of TRA/TRB germline genes in pinnipeds and a sea otter, with comparisons to terrestrial carnivores, artiodactyls, primates, rodents, reptiles, and ray-finned fishes. The dataset includes structural modeling and transcriptome-based repertoire analysis, supporting findings on gene conservation and contraction. It was authored by Huan Qin and last updated on 2026-04-16.

Use Cases

• Comparative analysis of germline gene expansion–contraction dynamics across vertebrate lineages based on the described phylogenetic and synteny data.
• Modeling T cell receptor structural conservation based on the described TRAC/TRBC stability findings.
• Analyzing repertoire diversity relative to germline copy number based on the described transcriptome-based usage patterns.
• Investigating lineage-specific patterns in TRBV gene proliferation within carnivorans based on the described phylogeny.

Strengths

• First systematic annotation of TRA/TRB genes for the specified pinniped species (Eumetopias jubatus, Zalophus californianus, Mirounga angustirostris, Neomonachus schauinslandi) and sea otter.
• Comparative analysis includes data from multiple vertebrate groups: terrestrial carnivores, artiodactyls, primates, rodents, reptiles, and ray-finned fishes.
• Includes structural modeling and transcriptome-based repertoire data as described.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is provided as a 4.0 MB DOCX file, which may require format conversion for computational analysis.

Provenance

Source

figshare

Collection Method

Systematic annotation and comparative analysis from genomic data, as described.

Time Range

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Freshness

Last updated 2026-04-16 04:20:22; freshness should be verified.

Geography

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