Data Sheet 1_Antibacterial effects of epigallocatechin gallate against calf diarrhea-causi

Yu Ren's study screened 10 plant extracts for antibacterial activity against a calf diarrhea-causing Escherichia coli strain. Epigallocatechin gallate (EGCG) showed the largest inhibition zone (19.7 ± 0.3 mm) and was tested in vivo on mice infected with E. coli. The research was uploaded to figshare on 2026-04-09.

Use Cases

• Analyze antibacterial efficacy based on inhibition zone, MIC, and MBC measurements
• Evaluate protective effects on intestinal injury based on bacterial load quantification
• Study expression of tight junction proteins (ZO-1, Occludin, Claudin-1) based on immunohistochemistry and Western blotting results

Strengths

• Specific in vitro results: inhibition zone of 19.7 ± 0.3 mm, MIC of 3.125 mg/mL, MBC of 50 mg/mL
• In vivo results include bacterial load quantification in liver and small intestine
• Analysis includes pathological evaluation and protein expression data

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect methodological bias inherent to the specific experimental setup

Provenance

Source

figshare

Collection Method

Experimental research involving disk diffusion assays, MIC/MBC tests, and in vivo mouse model studies.

Freshness

Last updated 2026-04-09 04:08:51