Antibiotic Prophylaxis in Percutaneous Nephrostomy for Cancer Patients with Meta-Analysis

A retrospective cohort study and systematic review investigating the association between antibiotic prophylaxis and urinary tract infections in cancer patients undergoing percutaneous nephrostomy procedures. The study includes data from 734 procedures and a meta-analysis of 19 studies involving 4,606 patients. The research was authored by Jeferson Rodrigo Zanon and last updated in May 2026.

Use Cases

• Assessing the effectiveness of antibiotic prophylaxis based on procedure type (catheter placement vs. replacement) mentioned in the results.
• Conducting meta-analyses on infection rates in percutaneous nephrostomy procedures using the included 19-study synthesis.
• Evaluating risk of bias in clinical studies on this topic, as the review notes a moderate to critical risk.
• Designing future randomized clinical trials based on the identified evidence gap discussed in the conclusion.

Strengths

• Includes primary data from 734 percutaneous nephrostomy procedures.
• Integrates a systematic review and meta-analysis of 19 studies with 4,606 patients.
• Provides specific infection rates (e.g., 0/158 with prophylaxis for placement, 4.5% without) and statistical measures like an odds ratio of 0.883.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a 105.1 KB document, suggesting limited raw data scope.
• The retrospective study design and noted risk of bias in included studies may limit causal inference.

Provenance

Source

figshare, authored by Jeferson Rodrigo Zanon.

Collection Method

Retrospective cohort study combined with a systematic review and meta-analysis.

Freshness

Last updated 2026-05-19 05:40:10; freshness should be verified.