Persulcatusin Antimicrobial Activity Data Against Vancomycin-Resistant Enterococcus

Persulcatusin exhibited a minimum inhibitory concentration of 0.625 μg/mL against vancomycin-resistant Enterococcus faecium strains. This research article by Ikki Morozumi, published on figshare in May 2026, details the peptide's species-specific efficacy and its distinct intracellular mechanism of action. The 1.2 MB PDF contains the full study results, including MIC values, killing assays, and DNA-binding analyses.

Use Cases

• Benchmarking antimicrobial peptide efficacy based on reported minimum inhibitory concentration (MIC) values
• Studying species-specific antibiotic mechanisms based on the described cellular penetration and DNA-binding assays
• Identifying potential drug candidates for vancomycin-resistant enterococci (VRE) infections based on the reported growth-inhibitory activity

Strengths

• Includes specific MIC values (e.g., 0.625 μg/mL) for direct potency comparison
• Mechanistic insights are provided from electron microscopy, localization, and DNA-binding assays
• Data is openly shared under a CC-BY-4.0 license

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is a 1.2 MB PDF, requiring manual extraction of structured data

Provenance

Source

figshare

Collection Method

Laboratory study involving clinical bacterial isolates, MIC determination, and mechanistic assays.

Time Range

Study publication date is 2026-05-04.

Freshness

Last updated 2026-05-04 05:30:35; freshness should be verified

Geography

Laboratory study; geographic origin of clinical isolates is unspecified.