Antimicrobial Stewardship Protocol for Neonatal ICUs in Suqian, China

A multicenter quality improvement study protocol outlines a bundled intervention to reduce antibiotic overuse in neonatal intensive care units. The study uses a before-and-after interrupted time series design across five NICUs in the Suqian region, collecting monthly aggregated data from 2025 to 2027. The protocol is authored by Bo Wang and is registered as a clinical trial (ChiCTR2600120301).

Use Cases

• Evaluating the impact of bundled quality improvement interventions based on the described standardized pathways and reassessment protocols.
• Analyzing interrupted time series trends in antibiotic use rates based on the monthly aggregated outcome data.
• Studying the implementation fidelity of clinical governance structures based on the described Plan-Do-Study-Act cycles and process adherence monitoring.

Strengths

• Protocol is registered with a clinical trial identifier (ChiCTR2600120301), providing a traceable research framework.
• Study design is explicitly described as a multicenter, before-and-after interrupted time series across five NICUs.
• Outcome and balancing measures are clearly defined, including antibiotic use rate and days of therapy per 1,000 patient-days.

Limitations

• The uploaded file is a 671.5 KB DOCX protocol document, not a dataset of clinical records; the underlying study data is not provided.
• Column-level documentation for any eventual study data is absent; field semantics must be inferred from the protocol.
• Row count for any eventual data is unknown, which limits suitability assessment for direct analysis.

Provenance

Source

figshare

Collection Method

Described as a multicenter study collecting monthly aggregated data from five neonatal intensive care units.

Time Range

Baseline period in 2025 and intervention period from 2026 to 2027.

Freshness

Last updated 2026-06-02 04:21:19; freshness should be verified as the document describes an ongoing study.

Geography

Suqian region, China.