Case Report of Crizotinib-Induced Aseptic Inflammatory Abscesses

A figshare-hosted case report details adverse events in a patient with ALK-rearranged lung adenocarcinoma. The report describes a 34-year-old female patient who developed aseptic inflammatory abscesses in the back and kidney after two years of crizotinib therapy. Authored by Hongyin Huang and last updated in May 2026, the 392.3 KB PDF document aims to fill a gap in understanding of this specific adverse drug reaction.

Use Cases

• Study rare adverse drug reaction patterns based on the detailed clinical timeline and patient history.
• Inform differential diagnosis for inflammatory masses in cancer patients based on the described imaging and pathology findings.
• Guide personalized treatment plan adjustments based on the case's outcome of dose reduction and symptom management.

Strengths

• The report provides a detailed, longitudinal clinical timeline spanning two years of treatment and follow-up.
• It includes specific pathological and radiographic findings that differentiate the condition from cancer metastasis.
• The dataset is openly licensed under CC-BY-4.0 for reuse.

Limitations

• The dataset is a single case report, limiting statistical generalizability.
• Column-level documentation is absent; field semantics must be inferred after download.
• The data format is a PDF, which may require text extraction for computational analysis.

Provenance

Source

figshare

Collection Method

Clinical case report authored by Hongyin Huang.

Freshness

Last updated 2026-05-14 04:29:29; freshness should be verified.