Aspartic Acid and Calcium Formulations for Enamel Repair: In Vitro Study Results

A research article investigating aspartic acid-calcium formulations as a biomimetic alternative to fluoride for dental enamel remineralization. The study, authored by Angelina Ivanova, uses an in vitro bovine enamel model to quantify surface microhardness recovery. The dataset was last updated on May 14, 2026, and is shared under a CC-BY-4.0 license.

Use Cases

• Compare the efficacy of different remineralization agents based on surface microhardness recovery data mentioned in the description.
• Analyze the statistical significance of treatment outcomes relative to a fluoride control as described in the results section.
• Investigate the role of calcium-binding amino acids in biomimetic material design based on the study's hypothesis.
• Benchmark novel dental repair formulations against conventional fluoride treatments using the provided experimental model.

Strengths

• The study design is clearly described, including demineralization conditions (pH 4.5 for 60 minutes) and treatment incubation (16 hours at 37°C).
• Specific quantitative results are reported, such as a mean %SMHR of 42.03 for one aspartic acid-calcium formulation.
• Statistical comparisons to a fluoride control are provided, with p-values like 0.0181 cited in the description.

Limitations

• The dataset is a 1.4 MB PDF; the underlying numerical data and column definitions are not directly accessible.
• Row count and data structure are unknown, which may limit suitability assessment for computational analysis.
• The data is from a specific in vitro model; clinical efficacy and underlying mechanisms require further investigation as noted in the conclusion.

Provenance

Source

Angelina Ivanova via figshare

Collection Method

Standardized in vitro bovine enamel model quantified by surface microhardness recovery (%SMHR).

Time Range

The study period is not specified.

Freshness

Last updated 2026-05-14 07:38:57; freshness should be verified.

Geography

The geographic origin of the research is not specified.