Serum and Follicular Fluid Oxytocin Levels and IVF Live Birth Outcomes

680 infertile patients undergoing IVF cycles between October 2024 and January 2025 were enrolled for this prospective cohort study. The data includes serum and follicular fluid oxytocin measurements, correlated with live birth rates and clinical parameters like lipid profiles and ovarian response markers. Ruiqiong Zhou authored the study, which was last updated on figshare in June 2026.

Use Cases

• Modeling the association between serum oxytocin levels and live birth rate based on the reported negative linear relationship.
• Analyzing correlations between follicular fluid oxytocin and ovarian response markers like hCG-trigger day estradiol and oocytes retrieved.
• Investigating the relationship between oxytocin levels and metabolic parameters such as triglycerides, LDL-C, HDL-C, and insulin.
• Comparing the predictive power of serum versus follicular fluid oxytocin for IVF outcomes using statistical approaches like multivariable logistic regression.

Strengths

• Includes data from 680 patients, providing a substantial cohort for analysis.
• Employs multiple statistical validation methods: multivariable logistic regression, inverse probability weighting, and a double robust model.
• Reports specific quantitative associations, such as a 37% decrease in live birth likelihood per 100 pg/mL serum oxytocin increase.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (144.3 KB), indicating limited scope or a summary document rather than raw patient-level data.

Provenance

Source

Ruiqiong Zhou

Collection Method

Prospective cohort study of patients undergoing IVF cycles.

Time Range

October 2024 to January 2025

Freshness

Last updated 2026-06-02 04:21:26; freshness should be verified.