Association Between Cholesterol Ratio and Carotid Plaque Risk in a 5,985-Person Cohort

5,985 adults from the Dalian Health Management Cohort (2015–2023) were tracked for carotid plaque development over a mean follow-up of 2.24 years. The study by Jingshan Jiang found a nonlinear positive association, with a 64% increased risk for those in the highest quartile of the non-HDL to HDL cholesterol ratio. This 800 KB PDF contains the underlying data for this retrospective cohort analysis.

Use Cases

• Modeling the risk of carotid plaque development based on the NHHR biomarker.
• Investigating effect modification by age, sex, and hypertension status as described in the results.
• Validating the NHHR inflection point of 4.071 for nonlinear risk association analysis.
• Conducting sensitivity and subgroup analyses to assess the robustness of epidemiological findings.

Strengths

• Includes data for 5,985 participants with a mean follow-up of 2.24 years, providing longitudinal insights.
• Results are supported by multiple analytical methods, including Cox models and restricted cubic spline analysis.
• Dataset is openly licensed under CC-BY-4.0, facilitating reuse and sharing.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying data tables is unknown, which may limit suitability assessment.
• Data reflects a specific cohort from Dalian, which may limit generalizability to other populations.

Provenance

Source

Dalian Health Management Cohort

Collection Method

Retrospective cohort study

Time Range

2015–2023

Freshness

Last updated 2026-04-28 04:29:21; freshness should be verified.

Geography

Dalian, China