TyG-BMI and Fracture Nonunion Risk in Older Patients, Multicenter Study 2020-2022

8,499 older patients from five tertiary hospitals were analyzed for fracture healing outcomes. The study found a U-shaped relationship between the metabolic indicator TyG-BMI and nonunion risk, with thresholds at 173.9 and 213.0. This retrospective cohort work by Xinqun Cheng investigates TyG-BMI as a biomarker for post-surgical risk stratification.

Use Cases

• Modeling fracture nonunion risk based on TyG-BMI levels and patient demographics.
• Investigating interactions between metabolic indicators and surgical factors like blood transfusion.
• Developing risk stratification tools for older patients undergoing limb fracture surgery.

Strengths

• Dataset includes 8,499 patient records from a multicenter study.
• Analysis identified specific risk thresholds (173.9 and 213.0) for the TyG-BMI indicator.
• Study employed sensitivity and subgroup analyses to evaluate robustness.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is stored in a DOCX file (412.5 KB), likely containing a manuscript rather than raw tabular data.

Provenance

Source

figshare

Collection Method

Multicenter retrospective cohort study.

Time Range

January 2020 to December 2022.

Freshness

Last updated 2026-04-24 04:21:12; freshness should be verified.

Geography

Data collected from five tertiary hospitals; specific locations unknown.