Data Sheet 1_Association between triglyceride glucose index and risk of acute kidney injur

A systematic review and meta-analysis aggregating results from 18 observational studies involving 81,479 critically ill patients. The work, authored by Maoying Wei and last updated in March 2026, investigates the association between the triglyceride-glucose index and the risk of acute kidney injury.

Use Cases

• Validate the triglyceride-glucose index as a predictor for acute kidney injury based on aggregated study results.
• Inform clinical guidelines for patient monitoring in critical care settings based on the reported pooled odds and hazard ratios.
• Support secondary analysis or modeling of insulin resistance markers in relation to renal complications.
• Serve as a foundational reference for designing new observational studies on metabolic syndrome and organ injury.

Strengths

• Includes a substantial pooled sample of 81,479 participants from 18 studies.
• Reports specific pooled effect sizes: an odds ratio of 1.39 and a hazard ratio of 1.43.
• Provides subgroup analysis details, such as results stratified by sex, age, and comorbidities.
• Has a registered systematic review protocol (CRD420251232658).

Limitations

• The primary data file is a DOCX document (6.1 MB); the underlying tabular data from the meta-analysis is not directly accessible.
• Column-level documentation and sample data are unavailable, requiring manual extraction from the report.
• The association was not statistically significant in all analyzed subgroups, such as the Black population.

Provenance

Source

figshare, authored by Maoying Wei.

Collection Method

Systematic literature review and meta-analysis of observational studies from PubMed, Embase, and Web of Science.

Time Range

Studies from database inception to October 31, 2025.

Freshness

Last updated 2026-03-18 07:38:20; literature search covered studies up to October 31, 2025.

Geography

Global, as the included studies are from international databases.