HALP Score Association with Comorbidity and Mortality in WCHAT and UK Biobank Cohorts

Two independent cohorts, totaling over 107,000 participants aged 50+, provide data for analyzing the hemoglobin-albumin-lymphocyte-platelet score. The study by Chaoxin Gao, published in 2026, found higher HALP scores were associated with lower risks of baseline and incident physical-cognitive comorbidity and lower all-cause mortality. The dataset likely contains participant-level clinical, laboratory, and functional measurements.

Use Cases

• Analyze associations between a composite biomarker score and health outcomes based on multivariable logistic regression results.
• Model incident physical-cognitive comorbidity risk based on longitudinal data from the WCHAT cohort.
• Predict all-cause mortality among individuals with baseline comorbidity based on Cox proportional hazards models from the UK Biobank.
• Perform subgroup and sensitivity analyses of biomarker associations based on the described methodology.

Strengths

• Includes data from two large cohorts: 5,957 participants from WCHAT and 101,655 from UK Biobank.
• Analysis covers multiple endpoints: baseline comorbidity, incident comorbidity, and all-cause mortality.
• Results are presented with specific odds ratios and hazard ratios, such as 0.77 (95% CI: 0.66–0.89) for baseline comorbidity in UKB.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data file is a DOCX document (84.8 KB), suggesting the dataset may be a summary or analysis output rather than raw participant data.

Provenance

Source

West China Health and Aging Trend (WCHAT) cohort and UK Biobank (UKB).

Collection Method

Data derived from cohort studies with laboratory, covariate, and functional measurements.

Freshness

Last updated 2026-05-22 04:30:20; freshness should be verified.

Geography

China (WCHAT) and United Kingdom (UK Biobank).