UK Biobank Data on Visceral Obesity Indices and Dementia Risk

A prospective cohort study of 327,368 dementia-free participants from the UK Biobank, with data collected up to 2026-05-18. The dataset examines associations between novel visceral obesity indices (METS-VF and BRI) and incident dementia, exploring the roles of metabolic mediators and genetic susceptibility. It was authored by Xinrui Xue and shared under a CC-BY-4.0 license.

Use Cases

• Modeling dementia risk based on visceral obesity indices like METS-VF and BRI.
• Investigating metabolic dysfunction as a potential mediator between obesity and dementia.
• Assessing the interaction between genetic susceptibility and visceral adiposity on dementia outcomes.
• Comparing the predictive value of novel obesity indices against conventional measures like BMI and waist circumference.

Strengths

• Includes data from a large prospective cohort of 327,368 participants.
• Validates obesity indices against imaging-derived visceral fat measures.
• Tracks 8,768 incident dementia cases during follow-up.
• Employs Cox proportional hazards models and restricted cubic spline analyses for robust statistical evaluation.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying analytical dataset is unknown, which may limit suitability assessment.
• The primary file is a 1.9 MB DOCX document, suggesting the data may be embedded in a manuscript rather than a standalone structured data file.

Provenance

Source

UK Biobank

Collection Method

Prospective cohort study

Freshness

Last updated 2026-05-18 05:35:50; freshness should be verified.

Geography

United Kingdom