Blood Sample Data on rDNA Copy Number and DNA Methylation for Myocardial Infarction

A dataset of 209 blood samples from myocardial infarction patients and healthy controls. It contains measurements of ribosomal DNA copy number and global DNA methylation, collected by Xiao Wang and published on figshare in May 2026. The data was used to assess associations with myocardial infarction risk.

Use Cases

• Assessing biomarker associations with myocardial infarction based on global DNA methylation levels.
• Evaluating the discriminative performance of biomarkers using ROC curve analysis.
• Investigating correlations between genetic/epigenetic markers and patient age.
• Training logistic regression models for disease classification using molecular data.

Strengths

• Includes 209 samples (100 MI patients, 109 healthy controls).
• Global DNA methylation demonstrated strong discriminative ability for MI (AUC = 0.97).
• Data is openly available under a CC-BY-4.0 license.

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The dataset is relatively small at 1.1 MB, which may limit statistical power for some analyses.
• The authors note further validation in larger populations is warranted.

Provenance

Source

figshare

Collection Method

Measurements from blood samples using Droplet Digital PCR (ddPCR) and ELISA.

Time Range

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Freshness

Last updated 2026-05-04 04:24:11.

Geography

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