T Cell and Protein Data from Myasthenia Gravis Thymic Hyperplasia Study

Xuemin Wang's 2026 figshare publication presents flow cytometry and western blotting results from a study on myasthenia gravis patients with thymic hyperplasia. The data includes measurements of Th1 and Th17 cell proportions in peripheral blood and thymus, along with protein expression levels of WNT4 and FOXN1. The study uses Pearson correlation to analyze links between autoreactive T cells and the thymic atrophy pathway.

Use Cases

• Correlate Th1 and Th17 cell proportions in peripheral blood and thymus with WNT4 and FOXN1 protein expression levels.
• Analyze the relationship between autoreactive T cell activity and the thymic atrophy pathway using the provided Pearson correlation results.
• Compare flow cytometry data for Th1 and Th17 cells between patient groups with and without myasthenia gravis.

Strengths

• Includes specific quantitative results, such as Th1 cell proportions of 1.207 ± 1.444 and 3.788 ± 0.6920 in different tissues.
• Focuses on a specific clinical cohort: patients with thymic hyperplasia and myasthenia gravis.
• Data is associated with a clear methodological description including flow cytometry and western blotting.

Limitations

• The underlying dataset is not directly accessible as tabular data; findings are presented within a 77.8 KB PDF document.
• Sample size for the patient cohort is not specified, limiting assessment of statistical power.
• Data is static from a single study with no indicated updates or expansions.

Provenance

Source

Xuemin Wang via figshare.

Collection Method

Samples obtained from surgical patients; analysis via flow cytometry for T cell subsets and western blotting for WNT4/FOXN1 proteins.

Freshness

Last updated March 23, 2026.