Data Sheet 1_Balancing oncologic risk and fertility potential: a single-center study on Tu

A clinical study of 224 Turner syndrome patients diagnosed between 2016 and 2024, authored by Xia Shuai. The research identifies Y-chromosome material in 11.6% of patients and analyzes associated gonadal tumor incidence and fertility potential using molecular genetics, histopathology, and endocrine profiling.

Use Cases

• Assessing malignancy risk in Turner syndrome patients based on the presence of Y-chromosome material.
• Evaluating fertility potential and ovarian reserve decline based on endocrine profiles like AMH levels.
• Comparing diagnostic accuracy of molecular genetic techniques versus karyotyping for detecting cryptic Y-material.
• Informing clinical decision-making for prophylactic gonadectomy based on tumor incidence and imaging findings.

Strengths

• Study includes 224 patient records from a defined period (2016-2024).
• Reports specific prevalence (11.6%) of Y-chromosome material and tumor incidence (25.0% in surgical cases).
• Analyzes multiple data dimensions: genetics, histopathology, endocrine profiles, and imaging.

Limitations

• Dataset is a 76.4 KB DOCX file; the underlying structured data (rows, columns) is unavailable for direct analysis.
• Row count and column-level documentation are unknown, limiting suitability assessment.
• Data is from a single-center study, which may limit generalizability.

Provenance

Source

figshare, author Xia Shuai.

Collection Method

Single-center clinical study utilizing molecular genetic techniques, histopathology, endocrine profiling, and pelvic imaging.

Time Range

Patients diagnosed between 2016 and 2024.

Freshness

Last updated 2026-05-05 10:37:09.