Bioinformatics Analysis of Bushen Anzhi Recipe for Aging-Related Insomnia

A 2026 dataset from figshare by Haiming Li, analyzing the mechanisms of a Traditional Chinese Medicine formula for insomnia. The data likely contains results from bioinformatics analysis of the GSE98582 gene expression dataset (555 samples) and experimental validation in a rat model (60 subjects).

Use Cases

• Identifying potential drug targets for insomnia based on overlapping neuroinflammatory and herbal component targets mentioned in the description.
• Analyzing gene interaction networks for core targets like HIF1A, PTGS2, and GSK3B as described in the study.
• Investigating the association between the Wnt signaling pathway and insomnia treatment efficacy as suggested by the results.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• Analysis is based on a public gene expression dataset (GSE98582) with 555 total samples.
• Includes experimental validation data from a controlled rat study with 60 subjects.

Limitations

• The dataset is very small at 6.7 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare, author Haiming Li.

Collection Method

Bioinformatics analysis of public gene expression data (GSE98582) and experimental results from a rat model study.

Time Range

The analysis and associated experimental work were likely conducted prior to the 2026 publication date.

Freshness

Last updated 2026-05-08 05:54:36.

Geography

The study likely originates from a Chinese research context, given the focus on Traditional Chinese Medicine.